STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107949761WD repeat and HMG-box DNA-binding protein 1-like. (975 aa)    
Predicted Functional Partners:
LOC107925704
Cell division control protein 45 homolog.
  
 
 0.995
LOC107897934
DNA polymerase.
   
 
 0.993
LOC107913234
DNA polymerase.
   
 
 0.993
LOC107913539
DNA helicase; Belongs to the MCM family.
   
 
 0.992
LOC107920789
DNA helicase; Belongs to the MCM family.
   
 
 0.992
LOC107907498
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
   
 
 0.990
LOC107907353
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
   
 
 0.990
LOC107912324
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.990
LOC107924650
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.990
LOC107905873
DNA helicase; Belongs to the MCM family.
   
 
 0.987
Your Current Organism:
Gossypium hirsutum
NCBI taxonomy Id: 3635
Other names: American cotton, American upland cotton, G. hirsutum, Gossypium hirsutum L., Gossypium hirsutum subsp. mexicanum, Gossypium hirsutum subsp. mexicanum (Tod.) Mauer, Gossypium lanceolatum, Gossypium lanceolatum Tod., Gossypium purpurascens, Gossypium purpurascens Poir., cotton
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