Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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tadAPutative nitrogen fixation symbiosis related protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa)    
Predicted Functional Partners:
tdk
Thymidine kinase; Identified by sequence similarity; putative.
 
  
 0.827
ribA
Riboflavin biosynthesis protein ribBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.823
ribB-2
Hypothetical protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
    
 0.823
ENN84561.1
Thymidine phosphorylase; Identified by sequence similarity; putative.
     
  0.770
hisE
phosphoribosyl-ATP pyrophosphatase; Identified by sequence similarity; putative.
   
  
 0.748
ENN88960.1
Putative methylase protein; Identified by sequence similarity; putative.
 
     0.743
thyA
Thymidylate synthase protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
 
 
 0.731
ENN85756.1
S-(hydroxymethyl)glutathione dehydrogenase; Identified by sequence similarity; putative; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 
  0.723
deoD
Purine-nucleoside phosphorylase protein; Identified by sequence similarity; putative.
    
 0.687
upp
Uracil phosphoribosyltransferase protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
 0.672
Your Current Organism:
Rhizobium freirei
NCBI taxonomy Id: 363754
Other names: R. freirei PRF 81, Rhizobium freirei PRF 81, Rhizobium sp. PRF 81
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