STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENN87323.1Chloride channel protein ClcB; Identified by sequence similarity; putative. (599 aa)    
Predicted Functional Partners:
ENN87322.1
Transcriptional regulator, MarR family; Identified by sequence similarity; putative.
 
     0.874
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
  
 0.853
gltB
Glutamate synthase, large subunit; Identified by sequence similarity; putative.
    
 0.804
ENN84664.1
Two-component sensor histidine kinase protein; Identified by sequence similarity; putative.
  
 
 0.782
ENN89806.1
2-oxoisovalerate dehydrogenase beta subunit protein; Identified by sequence similarity; putative.
    
 0.780
ENN84309.1
Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.771
ENN88028.1
Putative two-component sensor histidine kinase transcriptional regulatory protein; Identified by sequence similarity; putative.
  
 
 0.764
fumA
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.748
ENN89202.1
Putative two-component sensor histidine kinase/response regulator hybrid protein; Identified by sequence similarity; putative.
  
 
 0.725
ENN89368.1
Putative glutamine amidotransferase; Identified by sequence similarity; putative.
 
  
 0.718
Your Current Organism:
Rhizobium freirei
NCBI taxonomy Id: 363754
Other names: R. freirei PRF 81, Rhizobium freirei PRF 81, Rhizobium sp. PRF 81
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.