Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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guaAGlutamine amidotransferase protein; Identified by sequence similarity; putative. (242 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.980
gltB
Glutamate synthase, large subunit; Identified by sequence similarity; putative.
 
 
 0.937
ENN89357.1
Hypoxanthine phosphoribosyltransferase protein; Identified by sequence similarity; putative; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.893
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.872
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.872
gpt
Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
  
 
 0.865
ENN89615.1
Protein of unknown function DUF1332; Identified by sequence similarity; putative.
 
     0.857
ENN89368.1
Putative glutamine amidotransferase; Identified by sequence similarity; putative.
  
  
 
0.843
ENN87386.1
Putative 5'-nucleotidase protein; Identified by sequence similarity; putative; Belongs to the 5'-nucleotidase family.
     
 0.841
ENN89486.1
Putative HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
  0.840
Your Current Organism:
Rhizobium freirei
NCBI taxonomy Id: 363754
Other names: R. freirei PRF 81, Rhizobium freirei PRF 81, Rhizobium sp. PRF 81
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