Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ENN88136.1MutT/NUDIX family NTP pyrophosphohydrolase; Identified by sequence similarity; putative. (224 aa)    
Predicted Functional Partners:
nnrD
Putative carbohydrate kinase protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the re [...]
  
 0.839
ENN84664.1
Two-component sensor histidine kinase protein; Identified by sequence similarity; putative.
    
  0.764
ENN84175.1
Helicase domain protein; Identified by sequence similarity; putative.
    
 0.677
deaD
ATP-dependent RNA helicase protein; Identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
    
 0.677
rhlE
ATP-dependent RNA helicase protein; Identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
    
 0.677
noeJ
Mannose-1-phosphate guanylyltransferase (GDP) protein; Identified by sequence similarity; putative; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
  0.674
ribA
Riboflavin biosynthesis protein ribBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.667
ribB-2
Hypothetical protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
    
 0.667
rkpA
Putative type I polyketide synthase RkpA; Identified by sequence similarity; putative.
   
 0.652
ENN84634.1
Amino acid adenylation; Identified by sequence similarity; putative; overlaps another CDS with the same product name.
  
 0.628
Your Current Organism:
Rhizobium freirei
NCBI taxonomy Id: 363754
Other names: R. freirei PRF 81, Rhizobium freirei PRF 81, Rhizobium sp. PRF 81
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