Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
clpP-2Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (195 aa)    
Predicted Functional Partners:
clpX
ATP-dependent protease ATP-binding protein subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 0.995
clpB
ATP-dependent Clp protease, ATP-binding protein subunit protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
   
 
 0.886
clpA
ATP-dependent Clp protease protein, ATP-binding protein subunit; Identified by sequence similarity; putative; Belongs to the ClpA/ClpB family.
  
 
 0.880
groS
10 kDa chaperonin 2; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
 
 
 0.857
ENN87244.1
enoyl-CoA hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase; Identified by sequence similarity; putative.
    
  0.817
ENN88582.1
3-hydroxyacyl-CoA dehydrogenase, NAD-binding protein; Identified by sequence similarity; putative.
    
  0.817
ENN84025.1
Putative fatty oxidation complex subunit; Identified by sequence similarity; putative.
    
  0.817
groL
60 KDA chaperonin 1/GroEL protein 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 0.810
ENN89806.1
2-oxoisovalerate dehydrogenase beta subunit protein; Identified by sequence similarity; putative.
   
 0.808
ENN87093.1
Single-strand DNA binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 0.780
Your Current Organism:
Rhizobium freirei
NCBI taxonomy Id: 363754
Other names: R. freirei PRF 81, Rhizobium freirei PRF 81, Rhizobium sp. PRF 81
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.