Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENN89150.1Putative MutT/NUDIX family protein; Identified by sequence similarity; putative. (140 aa)    
Predicted Functional Partners:
rhlE
ATP-dependent RNA helicase protein; Identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
       0.741
gcvP
Glycine dehydrogenase decarboxylating; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.729
nadE
Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.721
ENN84664.1
Two-component sensor histidine kinase protein; Identified by sequence similarity; putative.
    
 0.621
metH
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.591
fumA
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.583
ENN85227.1
Nicotinate-nucleotide pyrophosphorylase; Identified by sequence similarity; putative; Belongs to the NadC/ModD family.
 
  
  0.574
thiD
Phosphomethylpyrimidine kinase; Identified by sequence similarity; putative.
  
 
  0.534
ribA
Riboflavin biosynthesis protein ribBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.531
ribB-2
Hypothetical protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
     
  0.531
Your Current Organism:
Rhizobium freirei
NCBI taxonomy Id: 363754
Other names: R. freirei PRF 81, Rhizobium freirei PRF 81, Rhizobium sp. PRF 81
Server load: low (16%) [HD]