Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENN86560.1Dimethylglycine dehydrogenase; Identified by sequence similarity; putative; Belongs to the GcvT family. (677 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase decarboxylating; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 0.997
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.980
ENN87429.1
Sarcosine oxidase delta subunit; Identified by sequence similarity; putative.
 
 0.969
ENN85434.1
Sarcosine oxidase, delta subunit family; Identified by sequence similarity; putative.
 
 0.967
soxD
Sarcosine oxidase protein, delta subunit; Identified by sequence similarity; putative.
 
 0.965
ENN87427.1
Sarcosine oxidase, gamma subunit family; Identified by sequence similarity; putative.
 
 0.948
ENN85432.1
Sarcosine oxidase gamma subunit; Identified by sequence similarity; putative.
 
 0.935
ENN89880.1
Sarcosine oxidase gamma subunit; Identified by sequence similarity; putative.
 
 0.934
ENN87428.1
Putative sarcosine oxidase alpha subunit; Identified by sequence similarity; putative.
 
0.933
ENN85433.1
Putative sarcosine oxidase alpha subunit; Identified by sequence similarity; putative.
 
0.933
Your Current Organism:
Rhizobium freirei
NCBI taxonomy Id: 363754
Other names: R. freirei PRF 81, Rhizobium freirei PRF 81, Rhizobium sp. PRF 81
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