| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KHD84599.1 | KHD84867.1 | NG54_14430 | NG54_12720 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.658 |
| KHD84599.1 | guaA | NG54_14430 | NG54_09510 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.576 |
| KHD84599.1 | murF | NG54_14430 | NG54_16805 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.983 |
| KHD84599.1 | murI | NG54_14430 | NG54_00755 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.551 |
| KHD84867.1 | KHD84599.1 | NG54_12720 | NG54_14430 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.658 |
| KHD84867.1 | KHD85792.1 | NG54_12720 | NG54_07090 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.732 |
| KHD84867.1 | murI | NG54_12720 | NG54_00755 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.663 |
| KHD85792.1 | KHD84867.1 | NG54_07090 | NG54_12720 | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.732 |
| KHD85792.1 | guaB | NG54_07090 | NG54_15355 | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.562 |
| KHD85792.1 | murI | NG54_07090 | NG54_00755 | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.728 |
| KHD86927.1 | guaA | NG54_00715 | NG54_09510 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.969 |
| KHD86927.1 | guaB | NG54_00715 | NG54_15355 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.861 |
| KHD86927.1 | murI | NG54_00715 | NG54_00755 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.940 |
| KHD86936.1 | KHD86937.1 | NG54_00760 | NG54_00765 | MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.523 |
| KHD86936.1 | murI | NG54_00760 | NG54_00755 | MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.886 |
| KHD86937.1 | KHD86936.1 | NG54_00765 | NG54_00760 | LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.523 |
| KHD86937.1 | murI | NG54_00765 | NG54_00755 | LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.520 |
| guaA | KHD84599.1 | NG54_09510 | NG54_14430 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.576 |
| guaA | KHD86927.1 | NG54_09510 | NG54_00715 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.969 |
| guaA | guaB | NG54_09510 | NG54_15355 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |