node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KHD85136.1 | KHD85525.1 | NG54_11190 | NG54_08635 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.687 |
KHD85136.1 | KHD85572.1 | NG54_11190 | NG54_08420 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.878 |
KHD85136.1 | ilvC | NG54_11190 | NG54_11195 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
KHD85136.1 | leuC | NG54_11190 | NG54_11210 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.960 |
KHD85136.1 | leuD | NG54_11190 | NG54_11215 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.965 |
KHD85364.1 | KHD85572.1 | NG54_09675 | NG54_08420 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.852 |
KHD85364.1 | KHD85575.1 | NG54_09675 | NG54_08435 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.611 |
KHD85364.1 | leuD | NG54_09675 | NG54_11215 | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.402 |
KHD85525.1 | KHD85136.1 | NG54_08635 | NG54_11190 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.687 |
KHD85525.1 | KHD85572.1 | NG54_08635 | NG54_08420 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.900 |
KHD85525.1 | ilvC | NG54_08635 | NG54_11195 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.992 |
KHD85525.1 | leuC | NG54_08635 | NG54_11210 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.958 |
KHD85525.1 | leuD | NG54_08635 | NG54_11215 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.978 |
KHD85571.1 | KHD85572.1 | NG54_08415 | NG54_08420 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.996 |
KHD85571.1 | KHD85573.1 | NG54_08415 | NG54_08425 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 4-oxalocrotonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.970 |
KHD85571.1 | KHD85575.1 | NG54_08415 | NG54_08435 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Catechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.827 |
KHD85571.1 | KHD85593.1 | NG54_08415 | NG54_08410 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
KHD85572.1 | KHD85136.1 | NG54_08420 | NG54_11190 | 4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.878 |
KHD85572.1 | KHD85364.1 | NG54_08420 | NG54_09675 | 4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.852 |
KHD85572.1 | KHD85525.1 | NG54_08420 | NG54_08635 | 4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |