STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsbDThiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (743 aa)    
Predicted Functional Partners:
SIN68113.1
Thioredoxin-related protein.
 
 
 0.974
SIO02374.1
Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.968
msrB
Peptide-methionine (R)-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family.
    
 
 0.932
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
    
 
 0.932
SIO05172.1
Transcriptional regulator, TetR family.
 
     0.710
SIO05142.1
Thioredoxin-related protein.
       0.658
SIO05192.1
Hypothetical protein.
       0.658
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
       0.524
SIO05109.1
UPF0716 protein FxsA.
       0.520
SIN68992.1
Peroxiredoxin (alkyl hydroperoxide reductase subunit C).
 
  
  0.499
Your Current Organism:
Sulfurivirga caldicuralii
NCBI taxonomy Id: 364032
Other names: DSM 17737, JCM 13439, S. caldicuralii, Sulfurivirga caldicuralii Takai et al. 2006, strain MM1
Server load: low (26%) [HD]