node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEV93064.1 | SEW19720.1 | SAMN04488515_0281 | SAMN04488515_1539 | L-threonine aldolase. | 5-aminolevulinate synthase. | 0.692 |
SEV93064.1 | gcvP | SAMN04488515_0281 | SAMN04488515_1481 | L-threonine aldolase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.944 |
SEV93064.1 | glyA | SAMN04488515_0281 | SAMN04488515_0429 | L-threonine aldolase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.908 |
SEW04047.1 | SEW10265.1 | SAMN04488515_0775 | SAMN04488515_1055 | [acyl-carrier-protein] S-malonyltransferase. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.726 |
SEW04047.1 | SEW19720.1 | SAMN04488515_0775 | SAMN04488515_1539 | [acyl-carrier-protein] S-malonyltransferase. | 5-aminolevulinate synthase. | 0.886 |
SEW04047.1 | glyA | SAMN04488515_0775 | SAMN04488515_0429 | [acyl-carrier-protein] S-malonyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.445 |
SEW10265.1 | SEW04047.1 | SAMN04488515_1055 | SAMN04488515_0775 | Porphobilinogen synthase; Belongs to the ALAD family. | [acyl-carrier-protein] S-malonyltransferase. | 0.726 |
SEW10265.1 | SEW19720.1 | SAMN04488515_1055 | SAMN04488515_1539 | Porphobilinogen synthase; Belongs to the ALAD family. | 5-aminolevulinate synthase. | 0.843 |
SEW19686.1 | SEW19703.1 | SAMN04488515_1537 | SAMN04488515_1538 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Uncharacterized conserved protein, DUF302 family. | 0.733 |
SEW19686.1 | SEW19720.1 | SAMN04488515_1537 | SAMN04488515_1539 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | 5-aminolevulinate synthase. | 0.625 |
SEW19686.1 | gcvP | SAMN04488515_1537 | SAMN04488515_1481 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.793 |
SEW19703.1 | SEW19686.1 | SAMN04488515_1538 | SAMN04488515_1537 | Uncharacterized conserved protein, DUF302 family. | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | 0.733 |
SEW19703.1 | SEW19720.1 | SAMN04488515_1538 | SAMN04488515_1539 | Uncharacterized conserved protein, DUF302 family. | 5-aminolevulinate synthase. | 0.773 |
SEW19720.1 | SEV93064.1 | SAMN04488515_1539 | SAMN04488515_0281 | 5-aminolevulinate synthase. | L-threonine aldolase. | 0.692 |
SEW19720.1 | SEW04047.1 | SAMN04488515_1539 | SAMN04488515_0775 | 5-aminolevulinate synthase. | [acyl-carrier-protein] S-malonyltransferase. | 0.886 |
SEW19720.1 | SEW10265.1 | SAMN04488515_1539 | SAMN04488515_1055 | 5-aminolevulinate synthase. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.843 |
SEW19720.1 | SEW19686.1 | SAMN04488515_1539 | SAMN04488515_1537 | 5-aminolevulinate synthase. | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | 0.625 |
SEW19720.1 | SEW19703.1 | SAMN04488515_1539 | SAMN04488515_1538 | 5-aminolevulinate synthase. | Uncharacterized conserved protein, DUF302 family. | 0.773 |
SEW19720.1 | SEW32654.1 | SAMN04488515_1539 | SAMN04488515_2341 | 5-aminolevulinate synthase. | L-idonate 5-dehydrogenase. | 0.640 |
SEW19720.1 | SEW42658.1 | SAMN04488515_1539 | SAMN04488515_2989 | 5-aminolevulinate synthase. | Signal transduction histidine kinase. | 0.710 |