node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEW04656.1 | SEW14932.1 | SAMN04488515_0802 | SAMN04488515_1285 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Citrate synthase; Belongs to the citrate synthase family. | 0.986 |
SEW04656.1 | SEW15798.1 | SAMN04488515_0802 | SAMN04488515_1324 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Dihydrolipoamide dehydrogenase. | 0.999 |
SEW04656.1 | SEW22242.1 | SAMN04488515_0802 | SAMN04488515_1686 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | NADPH-glutathione reductase. | 0.999 |
SEW04656.1 | SEW28877.1 | SAMN04488515_0802 | SAMN04488515_2047 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 2-oxoglutarate dehydrogenase E1 component. | 0.999 |
SEW04656.1 | SEW28896.1 | SAMN04488515_0802 | SAMN04488515_2048 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.999 |
SEW04656.1 | SEW28982.1 | SAMN04488515_0802 | SAMN04488515_2053 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Dihydrolipoamide dehydrogenase. | 0.999 |
SEW04656.1 | SEW47435.1 | SAMN04488515_0802 | SAMN04488515_3615 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | 0.999 |
SEW04656.1 | pdhA | SAMN04488515_0802 | SAMN04488515_0803 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
SEW04656.1 | sucC | SAMN04488515_0802 | SAMN04488515_2039 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.973 |
SEW04656.1 | sucD | SAMN04488515_0802 | SAMN04488515_2045 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.947 |
SEW14932.1 | SEW04656.1 | SAMN04488515_1285 | SAMN04488515_0802 | Citrate synthase; Belongs to the citrate synthase family. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.986 |
SEW14932.1 | SEW15798.1 | SAMN04488515_1285 | SAMN04488515_1324 | Citrate synthase; Belongs to the citrate synthase family. | Dihydrolipoamide dehydrogenase. | 0.427 |
SEW14932.1 | SEW22242.1 | SAMN04488515_1285 | SAMN04488515_1686 | Citrate synthase; Belongs to the citrate synthase family. | NADPH-glutathione reductase. | 0.415 |
SEW14932.1 | SEW28877.1 | SAMN04488515_1285 | SAMN04488515_2047 | Citrate synthase; Belongs to the citrate synthase family. | 2-oxoglutarate dehydrogenase E1 component. | 0.899 |
SEW14932.1 | SEW28896.1 | SAMN04488515_1285 | SAMN04488515_2048 | Citrate synthase; Belongs to the citrate synthase family. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.958 |
SEW14932.1 | SEW28982.1 | SAMN04488515_1285 | SAMN04488515_2053 | Citrate synthase; Belongs to the citrate synthase family. | Dihydrolipoamide dehydrogenase. | 0.427 |
SEW14932.1 | SEW47435.1 | SAMN04488515_1285 | SAMN04488515_3615 | Citrate synthase; Belongs to the citrate synthase family. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | 0.427 |
SEW14932.1 | sucC | SAMN04488515_1285 | SAMN04488515_2039 | Citrate synthase; Belongs to the citrate synthase family. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.995 |
SEW14932.1 | sucD | SAMN04488515_1285 | SAMN04488515_2045 | Citrate synthase; Belongs to the citrate synthase family. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.913 |
SEW15798.1 | SEW04656.1 | SAMN04488515_1324 | SAMN04488515_0802 | Dihydrolipoamide dehydrogenase. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.999 |