STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_0238TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: pol:Bpro_0298 HPrNtr. (89 aa)    
Predicted Functional Partners:
Pnap_0239
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
Pnap_0237
PFAM: PTS system fructose subfamily IIA component; KEGG: pol:Bpro_0297 PTS system fructose subfamily IIA component.
 
 
 0.994
hprK
Hpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
 
 
 0.859
Pnap_3793
TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: pol:Bpro_4612 PTS IIA-like nitrogen-regulatory protein PtsN.
 
  
 0.858
Pnap_0236
PFAM: major facilitator superfamily MFS_1; KEGG: pol:Bpro_0296 major facilitator superfamily MFS_1.
       0.799
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
  
 0.793
Pnap_0235
KEGG: pol:Bpro_0295 hypothetical protein.
       0.793
Pnap_2080
6-phosphofructokinase; PFAM: PfkB domain protein; KEGG: pol:Bpro_2756 PfkB; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.692
Pnap_0226
Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ccr:CC1137 transcriptional regulator, LacI family.
 
 
 
 0.570
Pnap_1493
Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: pol:Bpro_1738 transcriptional regulator, LacI family.
 
 
 
 0.559
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.