STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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[Homology]
Score
Pnap_0452KEGG: pol:Bpro_4195 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein. (519 aa)    
Predicted Functional Partners:
Pnap_0091
PAS/PAC sensor hybrid histidine kinase; KEGG: ana:alr3092 two-component hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 0.971
Pnap_4049
Multi-sensor signal transduction histidine kinase; KEGG: pol:Bpro_4825 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein.
 
 0.969
Pnap_1070
PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: psb:Psyr_2448 response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal.
 
 
 0.959
Pnap_1703
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.958
Pnap_0451
Response regulator receiver protein; TIGRFAM: DNA binding domain, excisionase family; PFAM: response regulator receiver; KEGG: pol:Bpro_4196 response regulator receiver domain protein (CheY-like).
 
 
 0.957
Pnap_1073
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE3 domain protein; KEGG: pfl:PFL_3251 sensor histidine kinase/response regulator.
 
 
 0.952
Pnap_0437
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: mca:MCA1204 sensory box histidine kinase/response regulator.
 
 
 
0.946
Pnap_2688
Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rme:Rmet_4855 periplasmic sensor hybrid histidine kinase.
 
 0.941
Pnap_3281
KEGG: rfr:Rfer_2271 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.929
Pnap_4048
PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: pol:Bpro_4824 response regulator receiver sensor signal transduction histidine kinase.
 
 
0.914
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.