node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnap_0690 | Pnap_0691 | Pnap_0690 | Pnap_0691 | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | 0.574 |
Pnap_0690 | Pnap_0692 | Pnap_0690 | Pnap_0692 | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | PFAM: ABC-2 type transporter; KEGG: pol:Bpro_0800 ABC-2. | 0.569 |
Pnap_0690 | Pnap_0693 | Pnap_0690 | Pnap_0693 | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | PFAM: BolA family protein; KEGG: pol:Bpro_0801 BolA-like protein; Belongs to the BolA/IbaG family. | 0.544 |
Pnap_0690 | hisB | Pnap_0690 | Pnap_0698 | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: pol:Bpro_0806 imidazoleglycerol-phosphate dehydratase. | 0.525 |
Pnap_0690 | hisC | Pnap_0690 | Pnap_0697 | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_0805 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.497 |
Pnap_0690 | hisD | Pnap_0690 | Pnap_0696 | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.545 |
Pnap_0690 | hisG | Pnap_0690 | Pnap_0695 | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.541 |
Pnap_0690 | hisH | Pnap_0690 | Pnap_0699 | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.469 |
Pnap_0690 | murA | Pnap_0690 | Pnap_0694 | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.541 |
Pnap_0691 | Pnap_0690 | Pnap_0691 | Pnap_0690 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | 0.574 |
Pnap_0691 | Pnap_0692 | Pnap_0691 | Pnap_0692 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | PFAM: ABC-2 type transporter; KEGG: pol:Bpro_0800 ABC-2. | 0.975 |
Pnap_0691 | Pnap_0693 | Pnap_0691 | Pnap_0693 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | PFAM: BolA family protein; KEGG: pol:Bpro_0801 BolA-like protein; Belongs to the BolA/IbaG family. | 0.735 |
Pnap_0691 | hisB | Pnap_0691 | Pnap_0698 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: pol:Bpro_0806 imidazoleglycerol-phosphate dehydratase. | 0.684 |
Pnap_0691 | hisC | Pnap_0691 | Pnap_0697 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_0805 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.674 |
Pnap_0691 | hisD | Pnap_0691 | Pnap_0696 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.725 |
Pnap_0691 | hisG | Pnap_0691 | Pnap_0695 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.787 |
Pnap_0691 | hisH | Pnap_0691 | Pnap_0699 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.612 |
Pnap_0691 | murA | Pnap_0691 | Pnap_0694 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.782 |
Pnap_0692 | Pnap_0690 | Pnap_0692 | Pnap_0690 | PFAM: ABC-2 type transporter; KEGG: pol:Bpro_0800 ABC-2. | KEGG: pol:Bpro_0798 anti-sigma-factor antagonist (STAS) domain protein. | 0.569 |
Pnap_0692 | Pnap_0691 | Pnap_0692 | Pnap_0691 | PFAM: ABC-2 type transporter; KEGG: pol:Bpro_0800 ABC-2. | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0799 ABC transporter related. | 0.975 |