node1 | node2 | node1 annotation | node2 annotation | score |
Pnap_0813 | Pnap_0814 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pol:Bpro_1337 serine/threonine protein kinase. | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | 0.967 |
Pnap_0813 | Pnap_0815 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pol:Bpro_1337 serine/threonine protein kinase. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.658 |
Pnap_0813 | Pnap_0816 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pol:Bpro_1337 serine/threonine protein kinase. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.555 |
Pnap_0813 | Pnap_0904 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pol:Bpro_1337 serine/threonine protein kinase. | KEGG: pol:Bpro_1298 hypothetical protein. | 0.737 |
Pnap_0813 | Pnap_1870 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pol:Bpro_1337 serine/threonine protein kinase. | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | 0.698 |
Pnap_0813 | Pnap_3062 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pol:Bpro_1337 serine/threonine protein kinase. | KEGG: pol:Bpro_3636 putative transmembrane protein. | 0.710 |
Pnap_0813 | Pnap_3949 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pol:Bpro_1337 serine/threonine protein kinase. | PFAM: Forkhead-associated protein; KEGG: pol:Bpro_4677 FHA domain containing protein. | 0.808 |
Pnap_0814 | Pnap_0813 | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pol:Bpro_1337 serine/threonine protein kinase. | 0.967 |
Pnap_0814 | Pnap_0815 | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.665 |
Pnap_0814 | Pnap_0816 | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.635 |
Pnap_0814 | Pnap_0904 | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | KEGG: pol:Bpro_1298 hypothetical protein. | 0.634 |
Pnap_0814 | Pnap_1784 | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment domain-containing protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: pol:Bpro_2669 dihydrolipoamide dehydrogenase. | 0.756 |
Pnap_0814 | Pnap_1786 | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: rfr:Rfer_2214 dihydrolipoamide dehydrogenase. | 0.756 |
Pnap_0814 | Pnap_1870 | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | 0.651 |
Pnap_0814 | Pnap_2683 | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: pol:Bpro_1868 glycine cleavage system T protein. | 0.624 |
Pnap_0814 | Pnap_3062 | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | KEGG: pol:Bpro_3636 putative transmembrane protein. | 0.614 |
Pnap_0814 | Pnap_3949 | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | PFAM: Forkhead-associated protein; KEGG: pol:Bpro_4677 FHA domain containing protein. | 0.757 |
Pnap_0815 | Pnap_0813 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pol:Bpro_1337 serine/threonine protein kinase. | 0.658 |
Pnap_0815 | Pnap_0814 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: protein phosphatase 2C domain protein; KEGG: pol:Bpro_1338 protein serine/threonine phosphatases. | 0.665 |
Pnap_0815 | Pnap_0816 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.821 |