STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_0902SMART: Tetratricopeptide domain protein; KEGG: pol:Bpro_1296 tetratricopeptide TPR_4. (625 aa)    
Predicted Functional Partners:
Pnap_0901
KEGG: pol:Bpro_1295 putative lipoprotein.
  
    0.833
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
       0.722
lptD
Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
   
 0.625
mutM
DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.613
Pnap_3630
Multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: pol:Bpro_4434 multi-sensor signal transduction histidine kinase.
  
     0.559
Pnap_3406
TIGRFAM: TonB family protein; KEGG: pol:Bpro_1088 TonB-like.
  
     0.546
bamA
Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
     0.523
Pnap_2847
PFAM: regulatory protein, MerR; KEGG: pol:Bpro_2109 transcriptional regulator, MerR family.
 
     0.517
Pnap_1925
PFAM: MotA/TolQ/ExbB proton channel; KEGG: pol:Bpro_2947 MotA/TolQ/ExbB proton channel.
 
     0.504
Pnap_0905
A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.
       0.500
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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