node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnap_1080 | murB | Pnap_1080 | Pnap_1081 | PFAM: protein of unknown function DUF520; KEGG: pol:Bpro_1596 protein of unknown function DUF520; Belongs to the UPF0234 family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.673 |
Pnap_4057 | murA | Pnap_4057 | Pnap_0694 | PFAM: Nucleotidyl transferase; KEGG: rfr:Rfer_0085 nucleotidyl transferase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.811 |
Pnap_4057 | murB | Pnap_4057 | Pnap_1081 | PFAM: Nucleotidyl transferase; KEGG: rfr:Rfer_0085 nucleotidyl transferase. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.902 |
Pnap_4057 | murC | Pnap_4057 | Pnap_3416 | PFAM: Nucleotidyl transferase; KEGG: rfr:Rfer_0085 nucleotidyl transferase. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.804 |
ddl | murA | Pnap_3415 | Pnap_0694 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.728 |
ddl | murB | Pnap_3415 | Pnap_1081 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.710 |
ddl | murC | Pnap_3415 | Pnap_3416 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
ddl | murD | Pnap_3415 | Pnap_3419 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.988 |
ddl | murE | Pnap_3415 | Pnap_3422 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.969 |
ddl | murG | Pnap_3415 | Pnap_3417 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.991 |
dxs | murB | Pnap_1501 | Pnap_1081 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.690 |
era | murB | Pnap_3060 | Pnap_1081 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.707 |
murA | Pnap_4057 | Pnap_0694 | Pnap_4057 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | PFAM: Nucleotidyl transferase; KEGG: rfr:Rfer_0085 nucleotidyl transferase. | 0.811 |
murA | ddl | Pnap_0694 | Pnap_3415 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | D-alanine--D-alanine ligase; Cell wall formation. | 0.728 |
murA | murB | Pnap_0694 | Pnap_1081 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.944 |
murA | murC | Pnap_0694 | Pnap_3416 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.847 |
murA | murD | Pnap_0694 | Pnap_3419 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.821 |
murA | murE | Pnap_0694 | Pnap_3422 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.819 |
murA | murG | Pnap_0694 | Pnap_3417 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.810 |
murB | Pnap_1080 | Pnap_1081 | Pnap_1080 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | PFAM: protein of unknown function DUF520; KEGG: pol:Bpro_1596 protein of unknown function DUF520; Belongs to the UPF0234 family. | 0.673 |