STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_1332TIGRFAM: thioredoxin; MJ0042 family finger-like protein; PFAM: Thioredoxin domain; KEGG: pol:Bpro_3369 thioredoxin. (159 aa)    
Predicted Functional Partners:
Pnap_1333
PFAM: cytochrome B561; KEGG: rfr:Rfer_2023 cytochrome b561.
       0.705
Pnap_3213
KEGG: pol:Bpro_3801 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.653
Pnap_2433
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pol:Bpro_2333 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.650
Pnap_1784
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment domain-containing protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: pol:Bpro_2669 dihydrolipoamide dehydrogenase.
  
 
 0.572
Pnap_1786
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: rfr:Rfer_2214 dihydrolipoamide dehydrogenase.
  
 
 0.572
Pnap_4070
L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
 0.562
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
  
 0.518
Pnap_3253
PFAM: heat shock protein DnaJ domain protein; KEGG: pol:Bpro_3897 heat shock protein DnaJ-like.
 
 
 0.472
Pnap_0683
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: pol:Bpro_0791 glutamate synthase (ferredoxin).
   
 
 0.468
Pnap_3544
NADPH-glutathione reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: pol:Bpro_0643 pyridine nucleotide-disulphide oxidoreductase dimerisation region.
  
 
 0.468
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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