STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_1551Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (312 aa)    
Predicted Functional Partners:
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
   
 0.942
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
   
 0.929
Pnap_1552
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pol:Bpro_4506 glyoxalase/bleomycin resistance protein/dioxygenase.
      0.835
Pnap_1553
PFAM: MaoC domain protein dehydratase; KEGG: pol:Bpro_4505 MaoC-like dehydratase.
 
     0.667
Pnap_1550
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pol:Bpro_4508 transcriptional regulator, LysR family.
 
     0.613
Pnap_4097
DNA-N1-methyladenine dioxygenase; PFAM: 2OG-Fe(II) oxygenase; KEGG: pol:Bpro_4875 2OG-Fe(II) oxygenase.
   
    0.469
Pnap_1554
PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: pol:Bpro_4504 L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family.
       0.444
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.444
Pnap_1560
4-hydroxyphenylpyruvate dioxygenase; PFAM: Xylose isomerase domain protein TIM barrel; KEGG: pol:Bpro_4496 4-hydroxyphenylpyruvate dioxygenase.
  
    0.408
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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