STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_1657TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase; PFAM: fumarate lyase; KEGG: pol:Bpro_1855 3-carboxy-cis,cis-muconate cycloisomerase. (404 aa)    
Predicted Functional Partners:
Pnap_2661
PFAM: Carboxymuconolactone decarboxylase; KEGG: pol:Bpro_1901 carboxymuconolactone decarboxylase.
 
 
 0.963
Pnap_2188
PFAM: Carboxymuconolactone decarboxylase; KEGG: mag:amb3965 uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
 
 
 0.941
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.936
Pnap_3811
3-carboxy-cis,cis-muconate cycloisomerase; PFAM: fumarate lyase; KEGG: pol:Bpro_4557 fumarate lyase.
  
  
 
0.916
Pnap_2121
3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; KEGG: pol:Bpro_1857 alpha/beta hydrolase fold.
 
   
 0.866
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.787
Pnap_1658
PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: pol:Bpro_4498 oxidoreductase-like.
       0.776
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.769
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
  
 0.766
purD
KEGG: pol:Bpro_1969 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family.
  
 
 0.764
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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