node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnap_1727 | Pnap_1728 | Pnap_1727 | Pnap_1728 | PFAM: protein of unknown function DUF853, NPT hydrolase putative; SMART: AAA ATPase; KEGG: pol:Bpro_1966 protein of unknown function DUF853, NPT hydrolase putative. | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | 0.597 |
Pnap_1727 | hemF | Pnap_1727 | Pnap_1730 | PFAM: protein of unknown function DUF853, NPT hydrolase putative; SMART: AAA ATPase; KEGG: pol:Bpro_1966 protein of unknown function DUF853, NPT hydrolase putative. | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.506 |
Pnap_1727 | purD | Pnap_1727 | Pnap_1729 | PFAM: protein of unknown function DUF853, NPT hydrolase putative; SMART: AAA ATPase; KEGG: pol:Bpro_1966 protein of unknown function DUF853, NPT hydrolase putative. | KEGG: pol:Bpro_1969 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.524 |
Pnap_1727 | upp | Pnap_1727 | Pnap_1726 | PFAM: protein of unknown function DUF853, NPT hydrolase putative; SMART: AAA ATPase; KEGG: pol:Bpro_1966 protein of unknown function DUF853, NPT hydrolase putative. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.656 |
Pnap_1728 | Pnap_1727 | Pnap_1728 | Pnap_1727 | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | PFAM: protein of unknown function DUF853, NPT hydrolase putative; SMART: AAA ATPase; KEGG: pol:Bpro_1966 protein of unknown function DUF853, NPT hydrolase putative. | 0.597 |
Pnap_1728 | Pnap_1734 | Pnap_1728 | Pnap_1734 | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.556 |
Pnap_1728 | aspS | Pnap_1728 | Pnap_0787 | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.718 |
Pnap_1728 | efp | Pnap_1728 | Pnap_1625 | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.598 |
Pnap_1728 | hemF | Pnap_1728 | Pnap_1730 | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.750 |
Pnap_1728 | purD | Pnap_1728 | Pnap_1729 | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | KEGG: pol:Bpro_1969 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.767 |
Pnap_1728 | rlmH | Pnap_1728 | Pnap_1733 | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.547 |
Pnap_1728 | rsfS | Pnap_1728 | Pnap_1732 | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.567 |
Pnap_1728 | ruvA | Pnap_1728 | Pnap_0510 | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.666 |
Pnap_1728 | upp | Pnap_1728 | Pnap_1726 | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.503 |
Pnap_1734 | Pnap_1728 | Pnap_1734 | Pnap_1728 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | 0.556 |
Pnap_1734 | hemF | Pnap_1734 | Pnap_1730 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.618 |
Pnap_1734 | purD | Pnap_1734 | Pnap_1729 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | KEGG: pol:Bpro_1969 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.616 |
Pnap_1734 | rlmH | Pnap_1734 | Pnap_1733 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.797 |
Pnap_1734 | rsfS | Pnap_1734 | Pnap_1732 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.804 |
aspS | Pnap_1728 | Pnap_0787 | Pnap_1728 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | PFAM: protein of unknown function DUF28; KEGG: pol:Bpro_1967 protein of unknown function DUF28. | 0.718 |