node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnap_1110 | Pnap_4108 | Pnap_1110 | Pnap_4108 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | KEGG: pol:Bpro_4898 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.882 |
Pnap_1110 | kdsA | Pnap_1110 | Pnap_1184 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: pol:Bpro_3182 2-dehydro-3-deoxyphosphooctonate aldolase. | 0.850 |
Pnap_1110 | kdsB | Pnap_1110 | Pnap_1921 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.984 |
Pnap_1110 | lpxB | Pnap_1110 | Pnap_1771 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.853 |
Pnap_1110 | lpxC | Pnap_1110 | Pnap_3411 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.852 |
Pnap_1110 | lpxD | Pnap_1110 | Pnap_1768 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.853 |
Pnap_1110 | lpxK | Pnap_1110 | Pnap_1923 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.998 |
Pnap_1922 | Pnap_1925 | Pnap_1922 | Pnap_1925 | PFAM: protein of unknown function DUF343; KEGG: pol:Bpro_2950 protein of unknown function DUF343; Belongs to the UPF0434 family. | PFAM: MotA/TolQ/ExbB proton channel; KEGG: pol:Bpro_2947 MotA/TolQ/ExbB proton channel. | 0.751 |
Pnap_1922 | kdsB | Pnap_1922 | Pnap_1921 | PFAM: protein of unknown function DUF343; KEGG: pol:Bpro_2950 protein of unknown function DUF343; Belongs to the UPF0434 family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.899 |
Pnap_1922 | lpxK | Pnap_1922 | Pnap_1923 | PFAM: protein of unknown function DUF343; KEGG: pol:Bpro_2950 protein of unknown function DUF343; Belongs to the UPF0434 family. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.935 |
Pnap_1925 | Pnap_1922 | Pnap_1925 | Pnap_1922 | PFAM: MotA/TolQ/ExbB proton channel; KEGG: pol:Bpro_2947 MotA/TolQ/ExbB proton channel. | PFAM: protein of unknown function DUF343; KEGG: pol:Bpro_2950 protein of unknown function DUF343; Belongs to the UPF0434 family. | 0.751 |
Pnap_1925 | Pnap_4108 | Pnap_1925 | Pnap_4108 | PFAM: MotA/TolQ/ExbB proton channel; KEGG: pol:Bpro_2947 MotA/TolQ/ExbB proton channel. | KEGG: pol:Bpro_4898 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.509 |
Pnap_1925 | kdsB | Pnap_1925 | Pnap_1921 | PFAM: MotA/TolQ/ExbB proton channel; KEGG: pol:Bpro_2947 MotA/TolQ/ExbB proton channel. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.856 |
Pnap_1925 | lpxB | Pnap_1925 | Pnap_1771 | PFAM: MotA/TolQ/ExbB proton channel; KEGG: pol:Bpro_2947 MotA/TolQ/ExbB proton channel. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.471 |
Pnap_1925 | lpxD | Pnap_1925 | Pnap_1768 | PFAM: MotA/TolQ/ExbB proton channel; KEGG: pol:Bpro_2947 MotA/TolQ/ExbB proton channel. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.549 |
Pnap_1925 | lpxK | Pnap_1925 | Pnap_1923 | PFAM: MotA/TolQ/ExbB proton channel; KEGG: pol:Bpro_2947 MotA/TolQ/ExbB proton channel. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.864 |
Pnap_4108 | Pnap_1110 | Pnap_4108 | Pnap_1110 | KEGG: pol:Bpro_4898 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.882 |
Pnap_4108 | Pnap_1925 | Pnap_4108 | Pnap_1925 | KEGG: pol:Bpro_4898 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | PFAM: MotA/TolQ/ExbB proton channel; KEGG: pol:Bpro_2947 MotA/TolQ/ExbB proton channel. | 0.509 |
Pnap_4108 | kdsA | Pnap_4108 | Pnap_1184 | KEGG: pol:Bpro_4898 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: pol:Bpro_3182 2-dehydro-3-deoxyphosphooctonate aldolase. | 0.989 |
Pnap_4108 | kdsB | Pnap_4108 | Pnap_1921 | KEGG: pol:Bpro_4898 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.885 |