node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnap_1953 | Pnap_1954 | Pnap_1953 | Pnap_1954 | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | 0.994 |
Pnap_1953 | Pnap_1955 | Pnap_1953 | Pnap_1955 | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: rfr:Rfer_4120 uptake hydrogenase accessory protein HupU. | 0.994 |
Pnap_1953 | Pnap_1966 | Pnap_1953 | Pnap_1966 | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | KEGG: rme:Rmet_1288 HupJ, contains rubredoxin domain. | 0.928 |
Pnap_1953 | Pnap_1967 | Pnap_1953 | Pnap_1967 | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: rme:Rmet_1289 rubredoxin-type Fe(Cys)4 protein; Belongs to the rubredoxin family. | 0.885 |
Pnap_1953 | Pnap_1968 | Pnap_1953 | Pnap_1968 | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: HupH hydrogenase expression protein; KEGG: rme:Rmet_1290 HupH hydrogenase expression protein. | 0.923 |
Pnap_1953 | Pnap_1969 | Pnap_1953 | Pnap_1969 | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: hydrogenase-1 expression HyaE; KEGG: rme:Rmet_1291 hydrogenase-1 expression HyaE; Belongs to the HupG/HyaE family. | 0.915 |
Pnap_1953 | Pnap_1970 | Pnap_1953 | Pnap_1970 | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: rme:Rmet_1292 hydrogenase assembly chaperone HypC/HupF. | 0.890 |
Pnap_1953 | Pnap_1971 | Pnap_1953 | Pnap_1971 | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | Hydrogenase 1 maturation peptidase HyaD, Aspartic peptidase, MEROPS family A31; TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; hydrogenase maturation peptidase superfamily; PFAM: peptidase M52, hydrogen uptake protein; KEGG: rme:Rmet_1293 hydrogenase expression/formation protein. | 0.864 |
Pnap_1953 | Pnap_1972 | Pnap_1953 | Pnap_1972 | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: rme:Rmet_1295 nickel-dependent hydrogenase b-type cytochrome subunit. | 0.749 |
Pnap_1953 | hypA | Pnap_1953 | Pnap_1964 | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.774 |
Pnap_1954 | Pnap_1953 | Pnap_1954 | Pnap_1953 | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | KEGG: rfr:Rfer_4122 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | 0.994 |
Pnap_1954 | Pnap_1955 | Pnap_1954 | Pnap_1955 | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: rfr:Rfer_4120 uptake hydrogenase accessory protein HupU. | 0.999 |
Pnap_1954 | Pnap_1966 | Pnap_1954 | Pnap_1966 | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | KEGG: rme:Rmet_1288 HupJ, contains rubredoxin domain. | 0.938 |
Pnap_1954 | Pnap_1967 | Pnap_1954 | Pnap_1967 | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: rme:Rmet_1289 rubredoxin-type Fe(Cys)4 protein; Belongs to the rubredoxin family. | 0.900 |
Pnap_1954 | Pnap_1968 | Pnap_1954 | Pnap_1968 | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | PFAM: HupH hydrogenase expression protein; KEGG: rme:Rmet_1290 HupH hydrogenase expression protein. | 0.957 |
Pnap_1954 | Pnap_1969 | Pnap_1954 | Pnap_1969 | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | PFAM: hydrogenase-1 expression HyaE; KEGG: rme:Rmet_1291 hydrogenase-1 expression HyaE; Belongs to the HupG/HyaE family. | 0.951 |
Pnap_1954 | Pnap_1970 | Pnap_1954 | Pnap_1970 | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: rme:Rmet_1292 hydrogenase assembly chaperone HypC/HupF. | 0.886 |
Pnap_1954 | Pnap_1971 | Pnap_1954 | Pnap_1971 | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | Hydrogenase 1 maturation peptidase HyaD, Aspartic peptidase, MEROPS family A31; TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; hydrogenase maturation peptidase superfamily; PFAM: peptidase M52, hydrogen uptake protein; KEGG: rme:Rmet_1293 hydrogenase expression/formation protein. | 0.952 |
Pnap_1954 | Pnap_1972 | Pnap_1954 | Pnap_1972 | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: rme:Rmet_1295 nickel-dependent hydrogenase b-type cytochrome subunit. | 0.991 |
Pnap_1954 | hypA | Pnap_1954 | Pnap_1964 | PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase. | Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.961 |