STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_2409PFAM: pentapeptide repeat protein; KEGG: tel:tll0709 hypothetical protein. (885 aa)    
Predicted Functional Partners:
Pnap_4054
PFAM: protein kinase; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; SMART: serine/threonine protein kinase; KEGG: mxa:MXAN_4053 sensor histidine kinase.
 
  
 0.568
Pnap_2408
PFAM: pentapeptide repeat protein; KEGG: gvi:gll2892 hypothetical protein.
 
   
0.538
Pnap_2410
PFAM: NHL repeat containing protein; KEGG: bur:Bcep18194_C7374 YadA/haemagluttinin like protein.
       0.535
Pnap_0028
PFAM: von Willebrand factor, type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa; KEGG: sat:SYN_02036 von Willebrand factor type A like domain.
 
     0.467
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
 
 0.451
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.451
Pnap_1703
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
  
 0.435
Pnap_0437
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: mca:MCA1204 sensory box histidine kinase/response regulator.
 
  
 0.414
Pnap_1677
PFAM: Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: pol:Bpro_2278 lytic transglycosylase, catalytic.
   
 
 0.414
Pnap_1073
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE3 domain protein; KEGG: pfl:PFL_3251 sensor histidine kinase/response regulator.
 
 
 0.406
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.