STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mnmCProtein of unknown function DUF752; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. (637 aa)    
Predicted Functional Partners:
Pnap_2423
Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
       0.790
Pnap_1666
Sulfide dehydrogenase (flavocytochrome), flavoprotein subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: reu:Reut_A3261 twin-arginine translocation pathway signal.
  
 
 0.645
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
  
 0.557
Pnap_3033
KEGG: pol:Bpro_3601 succinate dehydrogenase, cytochrome b subunit.
  
    0.534
Pnap_2422
TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: pol:Bpro_2345 thiosulphate-binding protein.
       0.518
Pnap_1276
PFAM: pseudouridine synthase; KEGG: pol:Bpro_3457 pseudouridine synthase.
 
    0.513
Pnap_0832
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: rfr:Rfer_3264 4Fe-4S ferredoxin, iron-sulfur binding.
  
  
 0.512
mnmE
tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
  
 0.510
Pnap_0683
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: pol:Bpro_0791 glutamate synthase (ferredoxin).
  
  
 0.503
Pnap_2421
PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: rfr:Rfer_1780 NADPH-dependent FMN reductase.
 
     0.485
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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