STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_2446PFAM: UvrD/REP helicase; protein of unknown function DUF955; KEGG: vpa:VP1083 putative ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. (1141 aa)    
Predicted Functional Partners:
Pnap_2447
KEGG: ana:alr7503 unknown protein.
 
     0.907
Pnap_2448
PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ana:alr7504 unknown protein.
 
   
 0.858
Pnap_2445
KEGG: vpa:VP1082 hypothetical protein.
       0.821
Pnap_2443
KEGG: pfo:Pfl_5697 hypothetical protein.
 
     0.818
Pnap_2444
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: vpa:VP1081 hypothetical protein.
       0.798
Pnap_2442
PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: pfo:Pfl_5696 AAA ATPase, central region.
 
     0.797
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.659
Pnap_3263
PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: cfe:CF0624 DNA polymerase III epsilon chain.
  
  
 0.605
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
 
 0.538
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.526
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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