STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_2448PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ana:alr7504 unknown protein. (469 aa)    
Predicted Functional Partners:
Pnap_2447
KEGG: ana:alr7503 unknown protein.
 
     0.949
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.913
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.865
Pnap_2446
PFAM: UvrD/REP helicase; protein of unknown function DUF955; KEGG: vpa:VP1083 putative ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily.
 
   
 0.858
Pnap_0021
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: hch:HCH_00139 thiamine biosynthesis protein ThiS.
  
 
 0.850
Pnap_2227
TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: pol:Bpro_2194 thiamineS.
  
 
 0.787
Pnap_2226
PFAM: molybdopterin biosynthesis MoaE; KEGG: rfr:Rfer_1917 molybdopterin biosynthesis MoaE.
  
 0.777
Pnap_2442
PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: pfo:Pfl_5696 AAA ATPase, central region.
 
     0.711
Pnap_2443
KEGG: pfo:Pfl_5697 hypothetical protein.
 
    0.678
Pnap_3049
PFAM: peptidase S16, lon domain protein; KEGG: pol:Bpro_3619 peptidase S16, lon-like.
    
 0.665
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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