STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_3013PFAM: aldehyde dehydrogenase; KEGG: eba:ebA2242 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)    
Predicted Functional Partners:
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.925
Pnap_1230
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pol:Bpro_3129 alcohol dehydrogenase, zinc-binding; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.917
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 
 0.916
Pnap_1691
PFAM: aldehyde dehydrogenase; KEGG: pol:Bpro_2290 aldehyde dehydrogenase (NAD+).
  
  
 
0.913
Pnap_2299
PFAM: Alcohol dehydrogenase GroES domain protein; KEGG: pol:Bpro_1201 putative alcohol dehydrogenase-like oxidoreductase protein.
  
 
 0.911
Pnap_0073
PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase.
  
 
 0.905
Pnap_0726
PFAM: Pyrrolo-quinoline quinone; KEGG: reu:Reut_A1784 pyrrolo-quinoline quinone.
   
 
 0.902
Pnap_2700
Propionate CoA-transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
     
 0.900
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    
 0.872
Pnap_3016
KEGG: gka:GK3199 hypothetical protein.
 
    0.869
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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