STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (425 aa)    
Predicted Functional Partners:
kynB
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
 
 
 0.998
kynA
Tryptophan 2,3-dioxygenase holoenzyme / Tryptophan 2,3-dioxygenase apoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.998
Pnap_1830
Catalase; PFAM: ThiJ/PfpI domain protein; Catalase domain protein; KEGG: nmu:Nmul_A1515 catalase.
   
 
 0.902
Pnap_1993
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 
 0.902
Pnap_2662
PFAM: Catalase domain protein; KEGG: neu:NE1886 catalase; Belongs to the catalase family.
   
 
 0.902
Pnap_1120
KEGG: reu:Reut_B4501 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.543
Pnap_3621
PFAM: AMP-dependent synthetase and ligase; KEGG: pol:Bpro_0589 benzoate-CoA ligase family.
  
 0.517
Pnap_3617
PFAM: NADH:flavin oxidoreductase/NADH oxidase; monooxygenase, FAD-binding; KEGG: pol:Bpro_0593 NADH:flavin oxidoreductase/NADH oxidase.
 
  
 0.507
Pnap_3017
PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: pol:Bpro_3587 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
   0.475
Pnap_3021
PFAM: protein of unknown function DUF1449; KEGG: tbd:Tbd_2219 hypothetical protein.
       0.409
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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