node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnap_1016 | Pnap_1632 | Pnap_1016 | Pnap_1632 | KEGG: rfr:Rfer_0845 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 0.906 |
Pnap_1016 | Pnap_1718 | Pnap_1016 | Pnap_1718 | KEGG: rfr:Rfer_0845 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pol:Bpro_2318 acetolactate synthase, small subunit. | 0.968 |
Pnap_1016 | Pnap_2310 | Pnap_1016 | Pnap_2310 | KEGG: rfr:Rfer_0845 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: bxe:Bxe_B1438 putative homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.633 |
Pnap_1016 | ilvC | Pnap_1016 | Pnap_1719 | KEGG: rfr:Rfer_0845 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.698 |
Pnap_1016 | ilvD | Pnap_1016 | Pnap_2877 | KEGG: rfr:Rfer_0845 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | KEGG: pol:Bpro_2052 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.561 |
Pnap_1016 | leuA | Pnap_1016 | Pnap_1721 | KEGG: rfr:Rfer_0845 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.541 |
Pnap_1016 | leuC | Pnap_1016 | Pnap_3039 | KEGG: rfr:Rfer_0845 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.904 |
Pnap_1016 | leuD | Pnap_1016 | Pnap_3040 | KEGG: rfr:Rfer_0845 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.817 |
Pnap_1632 | Pnap_1016 | Pnap_1632 | Pnap_1016 | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | KEGG: rfr:Rfer_0845 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 0.906 |
Pnap_1632 | Pnap_1718 | Pnap_1632 | Pnap_1718 | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pol:Bpro_2318 acetolactate synthase, small subunit. | 0.968 |
Pnap_1632 | Pnap_2310 | Pnap_1632 | Pnap_2310 | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: bxe:Bxe_B1438 putative homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.622 |
Pnap_1632 | ilvC | Pnap_1632 | Pnap_1719 | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.736 |
Pnap_1632 | ilvD | Pnap_1632 | Pnap_2877 | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | KEGG: pol:Bpro_2052 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.565 |
Pnap_1632 | leuA | Pnap_1632 | Pnap_1721 | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.540 |
Pnap_1632 | leuC | Pnap_1632 | Pnap_3039 | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.881 |
Pnap_1632 | leuD | Pnap_1632 | Pnap_3040 | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.816 |
Pnap_1718 | Pnap_1016 | Pnap_1718 | Pnap_1016 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pol:Bpro_2318 acetolactate synthase, small subunit. | KEGG: rfr:Rfer_0845 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 0.968 |
Pnap_1718 | Pnap_1632 | Pnap_1718 | Pnap_1632 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pol:Bpro_2318 acetolactate synthase, small subunit. | KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 0.968 |
Pnap_1718 | Pnap_2310 | Pnap_1718 | Pnap_2310 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pol:Bpro_2318 acetolactate synthase, small subunit. | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: bxe:Bxe_B1438 putative homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.582 |
Pnap_1718 | Pnap_3873 | Pnap_1718 | Pnap_3873 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: pol:Bpro_2318 acetolactate synthase, small subunit. | PFAM: pyruvate kinase; KEGG: pol:Bpro_4634 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.800 |