STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_3088PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX. (386 aa)    
Predicted Functional Partners:
Pnap_3089
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.999
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 
 0.979
Pnap_3087
PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein.
  
 0.973
Pnap_2151
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_2765 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.950
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.941
Pnap_1402
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pol:Bpro_3281 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.933
Pnap_2158
Cobalt-factor II C20-methyltransferase / precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
    
 0.908
Pnap_0192
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pol:Bpro_0245 porphobilinogen synthase; Belongs to the ALAD family.
  
 
 0.775
Pnap_3405
PFAM: ribonuclease II; KEGG: pol:Bpro_1089 ribonuclease II.
  
     0.731
Pnap_3897
KEGG: pol:Bpro_4655 hypothetical protein.
  
     0.708
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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