STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_3356PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: pol:Bpro_1134 putative phosphomethylpyrimidine kinase. (324 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.983
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
 
 0.973
Pnap_2435
KEGG: pol:Bpro_2331 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
  
  
 
0.929
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pol:Bpro_1133 glutamate-1-semialdehyde-2,1-aminomutase.
 
  
 0.862
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.734
Pnap_0021
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: hch:HCH_00139 thiamine biosynthesis protein ThiS.
  
    0.654
Pnap_3355
PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: pol:Bpro_1135 rubredoxin-type Fe(Cys)4 protein.
  
    0.605
Pnap_3353
PFAM: response regulator receiver; KEGG: pol:Bpro_1137 response regulator receiver domain protein (CheY-like).
  
    0.552
Pnap_3352
KEGG: pol:Bpro_1138 CheW-like protein.
 
     0.534
Pnap_3354
PFAM: response regulator receiver; KEGG: pol:Bpro_1136 response regulator receiver domain protein (CheY-like).
  
    0.530
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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