node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnap_0913 | Pnap_3359 | Pnap_0913 | Pnap_3359 | PFAM: BLUF domain protein; KEGG: pol:Bpro_0870 sensors of blue-light using FAD. | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | 0.850 |
Pnap_3359 | Pnap_0913 | Pnap_3359 | Pnap_0913 | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | PFAM: BLUF domain protein; KEGG: pol:Bpro_0870 sensors of blue-light using FAD. | 0.850 |
Pnap_3359 | Pnap_3361 | Pnap_3359 | Pnap_3361 | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | KEGG: pol:Bpro_1129 hypothetical protein. | 0.582 |
Pnap_3359 | dusA | Pnap_3359 | Pnap_2388 | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | tRNA-U16,U17-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | 0.679 |
Pnap_3359 | dusB | Pnap_3359 | Pnap_3360 | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.977 |
Pnap_3359 | dusC | Pnap_3359 | Pnap_1302 | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | tRNA-U20a,U20b-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | 0.679 |
Pnap_3359 | hfq | Pnap_3359 | Pnap_1877 | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.438 |
Pnap_3359 | lptD | Pnap_3359 | Pnap_4076 | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.441 |
Pnap_3359 | priB | Pnap_3359 | Pnap_2394 | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | Putative primosomal replication protein; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. | 0.553 |
Pnap_3359 | purH | Pnap_3359 | Pnap_3358 | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | KEGG: pol:Bpro_1132 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region. | 0.728 |
Pnap_3359 | rpsR | Pnap_3359 | Pnap_2393 | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.478 |
Pnap_3361 | Pnap_3359 | Pnap_3361 | Pnap_3359 | KEGG: pol:Bpro_1129 hypothetical protein. | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | 0.582 |
Pnap_3361 | dusB | Pnap_3361 | Pnap_3360 | KEGG: pol:Bpro_1129 hypothetical protein. | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.652 |
Pnap_3361 | purH | Pnap_3361 | Pnap_3358 | KEGG: pol:Bpro_1129 hypothetical protein. | KEGG: pol:Bpro_1132 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region. | 0.491 |
dusA | Pnap_3359 | Pnap_2388 | Pnap_3359 | tRNA-U16,U17-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | 0.679 |
dusB | Pnap_3359 | Pnap_3360 | Pnap_3359 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | 0.977 |
dusB | Pnap_3361 | Pnap_3360 | Pnap_3361 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | KEGG: pol:Bpro_1129 hypothetical protein. | 0.652 |
dusB | purH | Pnap_3360 | Pnap_3358 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | KEGG: pol:Bpro_1132 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region. | 0.732 |
dusB | rpsR | Pnap_3360 | Pnap_2393 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.468 |
dusC | Pnap_3359 | Pnap_1302 | Pnap_3359 | tRNA-U20a,U20b-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | DNA-binding protein Fis; PFAM: helix-turn-helix, Fis-type; KEGG: pol:Bpro_1131 transcriptional regulator, fis family; Belongs to the transcriptional regulatory Fis family. | 0.679 |