node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnap_0437 | Pnap_3513 | Pnap_0437 | Pnap_3513 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: mca:MCA1204 sensory box histidine kinase/response regulator. | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: pol:Bpro_4046 periplasmic sensor signal transduction histidine kinase. | 0.924 |
Pnap_0437 | Pnap_3515 | Pnap_0437 | Pnap_3515 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: mca:MCA1204 sensory box histidine kinase/response regulator. | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | 0.578 |
Pnap_0437 | gcvP | Pnap_0437 | Pnap_2685 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: mca:MCA1204 sensory box histidine kinase/response regulator. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.498 |
Pnap_2683 | Pnap_3515 | Pnap_2683 | Pnap_3515 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: pol:Bpro_1868 glycine cleavage system T protein. | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | 0.512 |
Pnap_2683 | gcvP | Pnap_2683 | Pnap_2685 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: pol:Bpro_1868 glycine cleavage system T protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
Pnap_2683 | purL | Pnap_2683 | Pnap_1821 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: pol:Bpro_1868 glycine cleavage system T protein. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.421 |
Pnap_2863 | Pnap_3515 | Pnap_2863 | Pnap_3515 | PFAM: aminotransferase class-III; KEGG: rfr:Rfer_0351 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | 0.462 |
Pnap_2863 | bioB | Pnap_2863 | Pnap_4030 | PFAM: aminotransferase class-III; KEGG: rfr:Rfer_0351 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.968 |
Pnap_2863 | bioD | Pnap_2863 | Pnap_4031 | PFAM: aminotransferase class-III; KEGG: rfr:Rfer_0351 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.851 |
Pnap_3513 | Pnap_0437 | Pnap_3513 | Pnap_0437 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: pol:Bpro_4046 periplasmic sensor signal transduction histidine kinase. | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: mca:MCA1204 sensory box histidine kinase/response regulator. | 0.924 |
Pnap_3513 | Pnap_3515 | Pnap_3513 | Pnap_3515 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: pol:Bpro_4046 periplasmic sensor signal transduction histidine kinase. | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | 0.926 |
Pnap_3515 | Pnap_0437 | Pnap_3515 | Pnap_0437 | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: mca:MCA1204 sensory box histidine kinase/response regulator. | 0.578 |
Pnap_3515 | Pnap_2683 | Pnap_3515 | Pnap_2683 | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: pol:Bpro_1868 glycine cleavage system T protein. | 0.512 |
Pnap_3515 | Pnap_2863 | Pnap_3515 | Pnap_2863 | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | PFAM: aminotransferase class-III; KEGG: rfr:Rfer_0351 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.462 |
Pnap_3515 | Pnap_3513 | Pnap_3515 | Pnap_3513 | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: pol:Bpro_4046 periplasmic sensor signal transduction histidine kinase. | 0.926 |
Pnap_3515 | Pnap_3516 | Pnap_3515 | Pnap_3516 | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | Thiosulfate sulfurtransferase; SMART: Rhodanese domain protein; KEGG: pol:Bpro_4049 rhodanese-like. | 0.494 |
Pnap_3515 | Pnap_4039 | Pnap_3515 | Pnap_4039 | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | PFAM: aminotransferase class-III; KEGG: rfr:Rfer_0373 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.469 |
Pnap_3515 | bioB | Pnap_3515 | Pnap_4030 | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.851 |
Pnap_3515 | bioD | Pnap_3515 | Pnap_4031 | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.916 |
Pnap_3515 | gcvP | Pnap_3515 | Pnap_2685 | PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_4048 glycine C-acetyltransferase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.500 |