STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmFmethylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1097 aa)    
Predicted Functional Partners:
Pnap_2383
KEGG: pol:Bpro_2161 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.
 
 
0.993
Pnap_2382
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: pol:Bpro_2163 LAO/AO transport system ATPase.
 
  
0.904
Pnap_0053
PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_0283 acetyl-CoA hydrolase/transferase.
  
  
 0.758
Pnap_0073
PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase.
  
  
 0.758
Pnap_3476
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: pol:Bpro_3956 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
 
  
 0.655
Pnap_2366
PFAM: periplasmic binding protein; KEGG: pol:Bpro_2784 periplasmic binding protein.
 
  
 0.654
Pnap_3887
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pol:Bpro_4647 pyruvate ferredoxin/flavodoxin oxidoreductase.
  
  
 0.608
Pnap_2364
PFAM: periplasmic binding protein; KEGG: pol:Bpro_2782 periplasmic binding protein.
  
  
 0.586
Pnap_1842
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: pol:Bpro_2573 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
  
  
 0.581
Pnap_2135
3-hydroxyacyl-CoA dehydrogenase; PFAM: Enoyl-CoA hydratase/isomerase; FAD dependent oxidoreductase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: reu:Reut_B3873 enoyl-CoA hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.581
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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