STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pnap_3750TIGRFAM: glutamate--cysteine ligase; KEGG: pol:Bpro_4583 glutamate--cysteine ligase GshA. (431 aa)    
Predicted Functional Partners:
gshB
KEGG: rfr:Rfer_0765 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase, ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
 
  
 0.948
secF
Protein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
 
 0.935
Pnap_3664
Uncharacterized enzyme; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
  
  
  0.915
Pnap_1068
Alanyl aminopeptidase, Metallo peptidase, MEROPS family M01; TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: pol:Bpro_1587 peptidase M1, alanyl aminopeptidase.
   
 
 0.910
pepA
Aminopeptidase A, Metallo peptidase, MEROPS family M17; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
    
 0.906
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 
  0.901
Pnap_1517
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinase B/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: pol:Bpro_1781 5-oxoprolinase (ATP-hydrolyzing).
    
  0.901
Pnap_1607
Gamma-glutamyltransferase 1, Threonine peptidase, MEROPS family T03; KEGG: pol:Bpro_3094 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
     
 0.901
gshA
TIGRFAM: glutamate--cysteine ligase; KEGG: pol:Bpro_3399 glutamate--cysteine ligase, monofunctional; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
Pnap_0683
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: pol:Bpro_0791 glutamate synthase (ferredoxin).
    
  0.833
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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