Pnap_3925 protein (Polaromonas naphthalenivorans)

Nodes:

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

Pnap_3925

KEGG: psp:PSPPH_4218 hypothetical protein. (555 aa)

Predicted Functional Partners:

Pnap_3926

0.838

Pnap_2467

0.556

Pnap_2522

0.554

Pnap_0416

0.544

Pnap_0422

0.532

Pnap_2468

0.528

Pnap_2521

0.528

Pnap_2464

0.490

Your Current Organism:

Polaromonas naphthalenivorans

NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
Pnap_0416	Pnap_0422	KEGG: rfr:Rfer_2711 transposase IS66.	PFAM: transposase IS66; KEGG: bxe:Bxe_B1865 transposase IS66 family.	0.980
Pnap_0416	Pnap_2464	KEGG: rfr:Rfer_2711 transposase IS66.	PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: pol:Bpro_5343 IstB-like ATP-binding protein.	0.428
Pnap_0416	Pnap_2522	KEGG: rfr:Rfer_2711 transposase IS66.	PFAM: IS66 Orf2 family protein; KEGG: reu:Reut_C6378 IS66 Orf2 like.	0.784
Pnap_0416	Pnap_3925	KEGG: rfr:Rfer_2711 transposase IS66.	KEGG: psp:PSPPH_4218 hypothetical protein.	0.544
Pnap_0422	Pnap_0416	PFAM: transposase IS66; KEGG: bxe:Bxe_B1865 transposase IS66 family.	KEGG: rfr:Rfer_2711 transposase IS66.	0.980
Pnap_0422	Pnap_2522	PFAM: transposase IS66; KEGG: bxe:Bxe_B1865 transposase IS66 family.	PFAM: IS66 Orf2 family protein; KEGG: reu:Reut_C6378 IS66 Orf2 like.	0.784
Pnap_0422	Pnap_3925	PFAM: transposase IS66; KEGG: bxe:Bxe_B1865 transposase IS66 family.	KEGG: psp:PSPPH_4218 hypothetical protein.	0.532
Pnap_2464	Pnap_0416	PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: pol:Bpro_5343 IstB-like ATP-binding protein.	KEGG: rfr:Rfer_2711 transposase IS66.	0.428
Pnap_2464	Pnap_2468	PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: pol:Bpro_5343 IstB-like ATP-binding protein.	PFAM: Integrase, catalytic region; KEGG: mxa:MXAN_3613 transposase, IS21 family.	0.824
Pnap_2464	Pnap_3925	PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: pol:Bpro_5343 IstB-like ATP-binding protein.	KEGG: psp:PSPPH_4218 hypothetical protein.	0.490
Pnap_2464	Pnap_3926	PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: pol:Bpro_5343 IstB-like ATP-binding protein.	PFAM: DNA-directed DNA polymerase; KEGG: psp:PSPPH_4219 DNA polymerase I domain protein.	0.408
Pnap_2467	Pnap_2468	PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:p1B4 IstB transposition helper protein.	PFAM: Integrase, catalytic region; KEGG: mxa:MXAN_3613 transposase, IS21 family.	0.962
Pnap_2467	Pnap_3925	PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:p1B4 IstB transposition helper protein.	KEGG: psp:PSPPH_4218 hypothetical protein.	0.556
Pnap_2467	Pnap_3926	PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:p1B4 IstB transposition helper protein.	PFAM: DNA-directed DNA polymerase; KEGG: psp:PSPPH_4219 DNA polymerase I domain protein.	0.408
Pnap_2468	Pnap_2464	PFAM: Integrase, catalytic region; KEGG: mxa:MXAN_3613 transposase, IS21 family.	PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: pol:Bpro_5343 IstB-like ATP-binding protein.	0.824
Pnap_2468	Pnap_2467	PFAM: Integrase, catalytic region; KEGG: mxa:MXAN_3613 transposase, IS21 family.	PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:p1B4 IstB transposition helper protein.	0.962
Pnap_2468	Pnap_3925	PFAM: Integrase, catalytic region; KEGG: mxa:MXAN_3613 transposase, IS21 family.	KEGG: psp:PSPPH_4218 hypothetical protein.	0.528
Pnap_2521	Pnap_2522	PFAM: transposase IS66; KEGG: reu:Reut_C6183 transposase IS66.	PFAM: IS66 Orf2 family protein; KEGG: reu:Reut_C6378 IS66 Orf2 like.	0.899
Pnap_2521	Pnap_3925	PFAM: transposase IS66; KEGG: reu:Reut_C6183 transposase IS66.	KEGG: psp:PSPPH_4218 hypothetical protein.	0.528
Pnap_2522	Pnap_0416	PFAM: IS66 Orf2 family protein; KEGG: reu:Reut_C6378 IS66 Orf2 like.	KEGG: rfr:Rfer_2711 transposase IS66.	0.784

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Network Stats

number of nodes:

11

number of edges:

33

average node degree:

6

avg. local clustering coefficient:

0.888

expected number of edges:

11

PPI enrichment p-value:

1.06e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032511

Late endosome to vacuole transport via multivesicular body sorting pathway

3 of 13

2.54

1.61

0.0011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:30572

Mixed, incl. Late endosome to vacuole transport via multivesicular body sorting pathway, and HCN channels

9 of 30

2.66

9.23

1.61e-19

CL:30574

Mixed, incl. Late endosome to vacuole transport via multivesicular body sorting pathway, and Polypeptide N-acetylgalactosaminyltransferase activity

8 of 18

2.83

9.07

2.19e-18

CL:30577

Mixed, incl. Synaptonemal complex protein 2-like, and Rab-GTPase-TBC domain

5 of 6

3.1

5.88

1.49e-11

CL:30595

Vps55/LEPROT, and Uncharacterised protein family UPF0220

3 of 5

2.96

2.81

7.42e-06

CL:19564

Dystrophin-associated glycoprotein complex, and EF-hand

2 of 14

2.33

0.87

0.0251

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016012

Sarcoglycan complex

2 of 5

2.78

1.04

0.0129

GOCC:0005927

Muscle tendon junction

2 of 6

2.7

1.04

0.0129

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF05255

Uncharacterised protein family (UPF0220)

2 of 2

3.18

1.3

0.0046

PF04790

Sarcoglycan complex subunit protein

2 of 5

2.78

1.15

0.0081

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007919

Uncharacterised protein family UPF0220

2 of 2

3.18

1.02

0.0145

IPR039972

Sarcoglycan gamma/delta/zeta

2 of 4

2.88

0.97

0.0181

IPR006875

Sarcoglycan complex subunit protein

2 of 5

2.78

0.96

0.0181

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