node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnap_0073 | Pnap_1782 | Pnap_0073 | Pnap_1782 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.910 |
Pnap_0073 | Pnap_1857 | Pnap_0073 | Pnap_1857 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.910 |
Pnap_0073 | Pnap_2383 | Pnap_0073 | Pnap_2383 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase. | KEGG: pol:Bpro_2161 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | 0.926 |
Pnap_0073 | Pnap_3032 | Pnap_0073 | Pnap_3032 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: pol:Bpro_3600 succinate dehydrogenase, cytochrome b subunit. | 0.906 |
Pnap_0073 | Pnap_3033 | Pnap_0073 | Pnap_3033 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase. | KEGG: pol:Bpro_3601 succinate dehydrogenase, cytochrome b subunit. | 0.900 |
Pnap_0073 | Pnap_3034 | Pnap_0073 | Pnap_3034 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase. | KEGG: pol:Bpro_3602 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.908 |
Pnap_0073 | Pnap_3035 | Pnap_0073 | Pnap_3035 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase. | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: pol:Bpro_3603 succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.917 |
Pnap_0073 | sucC | Pnap_0073 | Pnap_3953 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.933 |
Pnap_0073 | sucD | Pnap_0073 | Pnap_3952 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.929 |
Pnap_1782 | Pnap_0073 | Pnap_1782 | Pnap_0073 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase. | 0.910 |
Pnap_1782 | Pnap_1856 | Pnap_1782 | Pnap_1856 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: pol:Bpro_2624 2-oxoglutarate dehydrogenase, E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region. | 0.994 |
Pnap_1782 | Pnap_2383 | Pnap_1782 | Pnap_2383 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: pol:Bpro_2161 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | 0.821 |
Pnap_1782 | Pnap_3032 | Pnap_1782 | Pnap_3032 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: pol:Bpro_3600 succinate dehydrogenase, cytochrome b subunit. | 0.475 |
Pnap_1782 | Pnap_3034 | Pnap_1782 | Pnap_3034 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: pol:Bpro_3602 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.436 |
Pnap_1782 | Pnap_3035 | Pnap_1782 | Pnap_3035 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: pol:Bpro_3603 succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.600 |
Pnap_1782 | sucC | Pnap_1782 | Pnap_3953 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.949 |
Pnap_1782 | sucD | Pnap_1782 | Pnap_3952 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.942 |
Pnap_1856 | Pnap_1782 | Pnap_1856 | Pnap_1782 | KEGG: pol:Bpro_2624 2-oxoglutarate dehydrogenase, E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.994 |
Pnap_1856 | Pnap_1857 | Pnap_1856 | Pnap_1857 | KEGG: pol:Bpro_2624 2-oxoglutarate dehydrogenase, E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.999 |
Pnap_1856 | Pnap_3032 | Pnap_1856 | Pnap_3032 | KEGG: pol:Bpro_2624 2-oxoglutarate dehydrogenase, E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: pol:Bpro_3600 succinate dehydrogenase, cytochrome b subunit. | 0.885 |