Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrFCandidate Orotidine 5 -phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (291 aa)    
Predicted Functional Partners:
pyrE
Candidate Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.998
pyrR
Candidate bifunctional protein : Pyrimidine operon attenuation regulatory protein; Uracil phosphoribosyltransferase.
  
 
 0.985
upp
Candidate uracil phosphoribosyltransferase (UMP pyrophosphorylase); Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.939
pyrH
Uridylate kinase (Uridine monophosphate kinase)-like protein; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.932
surE
Candidate acid phosphatase (Stationary-phase survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.922
pyrD
Candidate dihydroorotate dehydrogenase (Dihydroorotate oxidase); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
  
 0.918
carB
Candidate carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthase (ammonia)); Belongs to the CarB family.
  
  
 0.906
pyrB
Candidate aspartate carbamoyltransferase (Aspartate transcarbamylase); Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.906
carA
Candidate carbamoyl-phosphate synthase small chain (Carbamoyl-phosphate synthase (glutamine-hydrolyzing)); Belongs to the CarA family.
  
  
 0.904
Rta_21145
Candidate septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
  0.900
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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