Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemBCandidate Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (336 aa)    
Predicted Functional Partners:
hemC
Pre-uroporphyrinogen synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.996
hemL
Candidate glutamate-1-semialdehyde 2,1-aminomutase (Glutamate-1-semialdehyde aminotransferase).
 
 
 0.992
Rta_26650
Uroporphyrinogen III methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.913
hemA
Candidate glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.873
Rta_28670
Hydroxymethylbilane hydrolyase (cyclizing); Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.849
corA-2
Candidate Mg2+ and Co2+ transporter.
       0.835
hemE
Candidate Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.832
Rta_03120
Conserved hypothetical protein.
       0.773
Rta_03130
Transcriptional regulator, LysR family-like protein; Belongs to the LysR transcriptional regulatory family.
       0.773
Rta_03160
Candidate membrane protein.
     
 0.666
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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