| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rta_07240 | coaX | Rta_07240 | Rta_08530 | Dihydroneopterin aldolase-like protein. | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.439 |
| Rta_08510 | Rta_08520 | Rta_08510 | Rta_08520 | Candidate histidine kinase, classic. | Transcriptional regulator, LuxR family-like protein. | 0.747 |
| Rta_08510 | coaX | Rta_08510 | Rta_08530 | Candidate histidine kinase, classic. | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.509 |
| Rta_08520 | Rta_08510 | Rta_08520 | Rta_08510 | Transcriptional regulator, LuxR family-like protein. | Candidate histidine kinase, classic. | 0.747 |
| Rta_08520 | coaX | Rta_08520 | Rta_08530 | Transcriptional regulator, LuxR family-like protein. | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.687 |
| Rta_25860 | coaX | Rta_25860 | Rta_08530 | Chaperone protein, HSP33 family-like protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.463 |
| birA | coaX | Rta_37510 | Rta_08530 | Candidate bifunctional protein (BirA) : transcriptional regulator (Biotin operon repressor), BirA family; Biotin-- [acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase). | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.913 |
| coaBC | coaD | Rta_25780 | Rta_33470 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Dephospho-CoA pyrophosphorylase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.947 |
| coaBC | coaX | Rta_25780 | Rta_08530 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.937 |
| coaD | coaBC | Rta_33470 | Rta_25780 | Dephospho-CoA pyrophosphorylase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.947 |
| coaD | coaX | Rta_33470 | Rta_08530 | Dephospho-CoA pyrophosphorylase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.942 |
| coaX | Rta_07240 | Rta_08530 | Rta_07240 | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Dihydroneopterin aldolase-like protein. | 0.439 |
| coaX | Rta_08510 | Rta_08530 | Rta_08510 | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Candidate histidine kinase, classic. | 0.509 |
| coaX | Rta_08520 | Rta_08530 | Rta_08520 | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Transcriptional regulator, LuxR family-like protein. | 0.687 |
| coaX | Rta_25860 | Rta_08530 | Rta_25860 | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Chaperone protein, HSP33 family-like protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. | 0.463 |
| coaX | birA | Rta_08530 | Rta_37510 | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Candidate bifunctional protein (BirA) : transcriptional regulator (Biotin operon repressor), BirA family; Biotin-- [acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase). | 0.913 |
| coaX | coaBC | Rta_08530 | Rta_25780 | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.937 |
| coaX | coaD | Rta_08530 | Rta_33470 | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Dephospho-CoA pyrophosphorylase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.942 |
| coaX | dac | Rta_08530 | Rta_03200 | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Candidate penicillin-binding protein precursor (D-alanyl-D-alanine carboxypeptidase); Belongs to the peptidase S11 family. | 0.427 |
| coaX | lolA | Rta_08530 | Rta_31640 | Bvg accessory factor-like protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Candidate Outer-membrane lipoproteins carrier protein precursor; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.429 |