| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rta_09420 | Rta_09430 | Rta_09420 | Rta_09430 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.801 |
| Rta_09420 | htpX | Rta_09420 | Rta_09440 | Conserved hypothetical protein. | Candidate heat shock protein, membrane protein; Belongs to the peptidase M48B family. | 0.551 |
| Rta_09420 | pyrC | Rta_09420 | Rta_09410 | Conserved hypothetical protein. | Candidate Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.815 |
| Rta_09430 | Rta_09420 | Rta_09430 | Rta_09420 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.801 |
| Rta_09430 | htpX | Rta_09430 | Rta_09440 | Conserved hypothetical protein. | Candidate heat shock protein, membrane protein; Belongs to the peptidase M48B family. | 0.625 |
| Rta_09430 | pyrC | Rta_09430 | Rta_09410 | Conserved hypothetical protein. | Candidate Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.835 |
| Rta_19350 | htpX | Rta_19350 | Rta_09440 | AAA-metalloprotease-like protein. | Candidate heat shock protein, membrane protein; Belongs to the peptidase M48B family. | 0.536 |
| Rta_24360 | htpX | Rta_24360 | Rta_09440 | Candidate membrane protein; Belongs to the BI1 family. | Candidate heat shock protein, membrane protein; Belongs to the peptidase M48B family. | 0.439 |
| Rta_36760 | clpB | Rta_36760 | Rta_23900 | Thioredoxin-like protein. | Candidate heat shock protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.449 |
| Rta_36760 | grpE | Rta_36760 | Rta_25070 | Thioredoxin-like protein. | Candidate heat shock protein, HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | 0.856 |
| Rta_36760 | htpX | Rta_36760 | Rta_09440 | Thioredoxin-like protein. | Candidate heat shock protein, membrane protein; Belongs to the peptidase M48B family. | 0.481 |
| clpB | Rta_36760 | Rta_23900 | Rta_36760 | Candidate heat shock protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Thioredoxin-like protein. | 0.449 |
| clpB | grpE | Rta_23900 | Rta_25070 | Candidate heat shock protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Candidate heat shock protein, HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | 0.853 |
| clpB | htpX | Rta_23900 | Rta_09440 | Candidate heat shock protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Candidate heat shock protein, membrane protein; Belongs to the peptidase M48B family. | 0.407 |
| grpE | Rta_36760 | Rta_25070 | Rta_36760 | Candidate heat shock protein, HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | Thioredoxin-like protein. | 0.856 |
| grpE | clpB | Rta_25070 | Rta_23900 | Candidate heat shock protein, HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | Candidate heat shock protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.853 |
| grpE | hflB1 | Rta_25070 | Rta_05130 | Candidate heat shock protein, HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | Candidate ATP-dependent Zn protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.468 |
| grpE | htpX | Rta_25070 | Rta_09440 | Candidate heat shock protein, HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | Candidate heat shock protein, membrane protein; Belongs to the peptidase M48B family. | 0.472 |
| hflB1 | grpE | Rta_05130 | Rta_25070 | Candidate ATP-dependent Zn protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Candidate heat shock protein, HSP70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | 0.468 |
| hflB1 | htpX | Rta_05130 | Rta_09440 | Candidate ATP-dependent Zn protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Candidate heat shock protein, membrane protein; Belongs to the peptidase M48B family. | 0.577 |
