| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dapF | lysA | Rta_09500 | Rta_07930 | Candidate Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Candidate Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.956 |
| dapF | murD | Rta_09500 | Rta_09680 | Candidate Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Candidate UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase (D-glutamic acid adding enzyme); Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.471 |
| dapF | murE | Rta_09500 | Rta_09640 | Candidate Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Candidate UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.952 |
| dapF | murF | Rta_09500 | Rta_09660 | Candidate Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Candidate UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.527 |
| ddlA | ftsI | Rta_09720 | Rta_09630 | Candidate D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Candidate cell division penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.934 |
| ddlA | mraW | Rta_09720 | Rta_09610 | Candidate D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Candidate S-adenosyl-methyltransferase (division cell wall cluster); Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.809 |
| ddlA | mraY | Rta_09720 | Rta_09670 | Candidate D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Candidate phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.924 |
| ddlA | murC | Rta_09720 | Rta_09710 | Candidate D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Candidate UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.998 |
| ddlA | murD | Rta_09720 | Rta_09680 | Candidate D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Candidate UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase (D-glutamic acid adding enzyme); Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.996 |
| ddlA | murE | Rta_09720 | Rta_09640 | Candidate D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Candidate UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.913 |
| ddlA | murF | Rta_09720 | Rta_09660 | Candidate D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Candidate UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.996 |
| ddlA | murG | Rta_09720 | Rta_09700 | Candidate D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.984 |
| ftsI | ddlA | Rta_09630 | Rta_09720 | Candidate cell division penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Candidate D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.934 |
| ftsI | mraW | Rta_09630 | Rta_09610 | Candidate cell division penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Candidate S-adenosyl-methyltransferase (division cell wall cluster); Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.925 |
| ftsI | mraY | Rta_09630 | Rta_09670 | Candidate cell division penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Candidate phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.943 |
| ftsI | murC | Rta_09630 | Rta_09710 | Candidate cell division penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Candidate UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.945 |
| ftsI | murD | Rta_09630 | Rta_09680 | Candidate cell division penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Candidate UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase (D-glutamic acid adding enzyme); Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.941 |
| ftsI | murE | Rta_09630 | Rta_09640 | Candidate cell division penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Candidate UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.990 |
| ftsI | murF | Rta_09630 | Rta_09660 | Candidate cell division penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Candidate UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.961 |
| ftsI | murG | Rta_09630 | Rta_09700 | Candidate cell division penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.913 |