Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metZCystathionine gamma-synthase (O-succinylhomoserine (Thiol)-lyase)-like protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (404 aa)    
Predicted Functional Partners:
metX
Homoserine transacetylase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
 
  
 0.964
metH
Candidate Methionine synthase.
  
 
 0.937
metE
Candidate Methylcobalamin:homocysteine methyltransferase (Methionine synthase).
  
 
 0.935
Rta_22600
Ferredoxin--nitrite reductase-like protein.
 
 
 0.935
Rta_14560
Candidate O-acetylhomoserine (Thiol)-lyase (O-acetylhomoserine sulfhydrylase); (Homocysteine synthase) (Methionine synthase).
 
 
0.929
purF
Candidate amidophosphoribosyltransferase (Glutamine phosphoribosylpyrophosphate amidotransferase); Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.927
Rta_19080
Cystathionine beta-lyase (Beta-cystathionase)-like protein; (Cysteine lyase) (Osteotoxin).
  
  
 
0.925
metH-2
Candidate methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.924
ahcY
Candidate Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.916
Rta_13730
Candidate sulfide dehydrogenase [flavocytochrome c] flavoprotein chain precursor.
  
 
 0.908
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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