| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rta_13660 | Rta_13670 | Rta_13660 | Rta_13670 | Prephenate dehydrogenase-like protein. | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | 0.994 |
| Rta_13660 | cmk | Rta_13660 | Rta_13650 | Prephenate dehydrogenase-like protein. | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | 0.995 |
| Rta_13660 | gyrA | Rta_13660 | Rta_13680 | Prephenate dehydrogenase-like protein. | Candidate DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.853 |
| Rta_13660 | rpsA | Rta_13660 | Rta_13640 | Prephenate dehydrogenase-like protein. | Candidate 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.705 |
| Rta_13670 | Rta_13660 | Rta_13670 | Rta_13660 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Prephenate dehydrogenase-like protein. | 0.994 |
| Rta_13670 | cmk | Rta_13670 | Rta_13650 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | 0.987 |
| Rta_13670 | gyrA | Rta_13670 | Rta_13680 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Candidate DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.892 |
| Rta_13670 | katG | Rta_13670 | Rta_04130 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Candidate hydroperoxidase I; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.800 |
| Rta_13670 | metG | Rta_13670 | Rta_30620 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Candidate methionyl-tRNA synthetase (Methionine--tRNA ligase); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.496 |
| Rta_13670 | rpsA | Rta_13670 | Rta_13640 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Candidate 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.777 |
| cmk | Rta_13660 | Rta_13650 | Rta_13660 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Prephenate dehydrogenase-like protein. | 0.995 |
| cmk | Rta_13670 | Rta_13650 | Rta_13670 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | 0.987 |
| cmk | gyrA | Rta_13650 | Rta_13680 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Candidate DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.866 |
| cmk | metG | Rta_13650 | Rta_30620 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Candidate methionyl-tRNA synthetase (Methionine--tRNA ligase); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.691 |
| cmk | rpsA | Rta_13650 | Rta_13640 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Candidate 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.794 |
| gyrA | Rta_13660 | Rta_13680 | Rta_13660 | Candidate DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Prephenate dehydrogenase-like protein. | 0.853 |
| gyrA | Rta_13670 | Rta_13680 | Rta_13670 | Candidate DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | 0.892 |
| gyrA | cmk | Rta_13680 | Rta_13650 | Candidate DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | 0.866 |
| gyrA | gyrB | Rta_13680 | Rta_00030 | Candidate DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Candidate DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.986 |
| gyrA | katG | Rta_13680 | Rta_04130 | Candidate DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Candidate hydroperoxidase I; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.752 |
