| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rta_13670 | cmk | Rta_13670 | Rta_13650 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | 0.987 |
| Rta_13670 | gph | Rta_13670 | Rta_13710 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Candidate phosphoglycolate phosphatase. | 0.442 |
| Rta_13670 | gyrA | Rta_13670 | Rta_13680 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Candidate DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.892 |
| Rta_13670 | ompA | Rta_13670 | Rta_13690 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Candidate outer membrane protein precursor. | 0.554 |
| Rta_13670 | purL | Rta_13670 | Rta_20330 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | Candidate phosphoribosylformylglycinamidine synthase (FGAM synthase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.531 |
| Rta_13670 | ubiG | Rta_13670 | Rta_13700 | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | DHHB methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.495 |
| Rta_37910 | anmK | Rta_37910 | Rta_07060 | Conserved hypothetical protein. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.409 |
| Rta_37910 | gph | Rta_37910 | Rta_13710 | Conserved hypothetical protein. | Candidate phosphoglycolate phosphatase. | 0.933 |
| anmK | Rta_37910 | Rta_07060 | Rta_37910 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Conserved hypothetical protein. | 0.409 |
| anmK | gph | Rta_07060 | Rta_13710 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Candidate phosphoglycolate phosphatase. | 0.905 |
| cmk | Rta_13670 | Rta_13650 | Rta_13670 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | 0.987 |
| cmk | gph | Rta_13650 | Rta_13710 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Candidate phosphoglycolate phosphatase. | 0.412 |
| cmk | gyrA | Rta_13650 | Rta_13680 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Candidate DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.866 |
| cmk | ompA | Rta_13650 | Rta_13690 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Candidate outer membrane protein precursor. | 0.531 |
| cmk | purL | Rta_13650 | Rta_20330 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | Candidate phosphoribosylformylglycinamidine synthase (FGAM synthase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.591 |
| cmk | ubiG | Rta_13650 | Rta_13700 | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | DHHB methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.431 |
| gph | Rta_13670 | Rta_13710 | Rta_13670 | Candidate phosphoglycolate phosphatase. | Candidate bifunctional protein: chorismate mutase; prephenate dehydratase. | 0.442 |
| gph | Rta_37910 | Rta_13710 | Rta_37910 | Candidate phosphoglycolate phosphatase. | Conserved hypothetical protein. | 0.933 |
| gph | anmK | Rta_13710 | Rta_07060 | Candidate phosphoglycolate phosphatase. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.905 |
| gph | cmk | Rta_13710 | Rta_13650 | Candidate phosphoglycolate phosphatase. | Deoxycytidine kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily. | 0.412 |