| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rta_14500 | Rta_14510 | Rta_14500 | Rta_14510 | D-lactate dehydrogenase (cytochrome)-like protein. | Candidate membrane protein. | 0.835 |
| Rta_14500 | Rta_14520 | Rta_14500 | Rta_14520 | D-lactate dehydrogenase (cytochrome)-like protein. | Candidate membrane protein. | 0.608 |
| Rta_14500 | folA | Rta_14500 | Rta_14480 | D-lactate dehydrogenase (cytochrome)-like protein. | Candidate dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.628 |
| Rta_14500 | thyA | Rta_14500 | Rta_14490 | D-lactate dehydrogenase (cytochrome)-like protein. | Candidate thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.637 |
| Rta_14500 | xthA | Rta_14500 | Rta_14470 | D-lactate dehydrogenase (cytochrome)-like protein. | Candidate exodeoxyribonuclease III. | 0.624 |
| Rta_14510 | Rta_14500 | Rta_14510 | Rta_14500 | Candidate membrane protein. | D-lactate dehydrogenase (cytochrome)-like protein. | 0.835 |
| Rta_14510 | Rta_14520 | Rta_14510 | Rta_14520 | Candidate membrane protein. | Candidate membrane protein. | 0.637 |
| Rta_14510 | folA | Rta_14510 | Rta_14480 | Candidate membrane protein. | Candidate dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.644 |
| Rta_14510 | thyA | Rta_14510 | Rta_14490 | Candidate membrane protein. | Candidate thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.642 |
| Rta_14510 | xthA | Rta_14510 | Rta_14470 | Candidate membrane protein. | Candidate exodeoxyribonuclease III. | 0.623 |
| Rta_14520 | Rta_14500 | Rta_14520 | Rta_14500 | Candidate membrane protein. | D-lactate dehydrogenase (cytochrome)-like protein. | 0.608 |
| Rta_14520 | Rta_14510 | Rta_14520 | Rta_14510 | Candidate membrane protein. | Candidate membrane protein. | 0.637 |
| Rta_14520 | folA | Rta_14520 | Rta_14480 | Candidate membrane protein. | Candidate dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.473 |
| Rta_14520 | thyA | Rta_14520 | Rta_14490 | Candidate membrane protein. | Candidate thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.475 |
| Rta_14520 | xthA | Rta_14520 | Rta_14470 | Candidate membrane protein. | Candidate exodeoxyribonuclease III. | 0.481 |
| folA | Rta_14500 | Rta_14480 | Rta_14500 | Candidate dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | D-lactate dehydrogenase (cytochrome)-like protein. | 0.628 |
| folA | Rta_14510 | Rta_14480 | Rta_14510 | Candidate dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Candidate membrane protein. | 0.644 |
| folA | Rta_14520 | Rta_14480 | Rta_14520 | Candidate dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Candidate membrane protein. | 0.473 |
| folA | thyA | Rta_14480 | Rta_14490 | Candidate dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Candidate thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| folA | xthA | Rta_14480 | Rta_14470 | Candidate dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Candidate exodeoxyribonuclease III. | 0.798 |