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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rta_14560Candidate O-acetylhomoserine (Thiol)-lyase (O-acetylhomoserine sulfhydrylase); (Homocysteine synthase) (Methionine synthase). (436 aa)    
Predicted Functional Partners:
metX
Homoserine transacetylase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
 
 
 0.988
Rta_19080
Cystathionine beta-lyase (Beta-cystathionase)-like protein; (Cysteine lyase) (Osteotoxin).
 
 
0.942
metH-2
Candidate methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.936
metH
Candidate Methionine synthase.
  
 
 0.932
metZ
Cystathionine gamma-synthase (O-succinylhomoserine (Thiol)-lyase)-like protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 
0.929
metE
Candidate Methylcobalamin:homocysteine methyltransferase (Methionine synthase).
  
 
 0.919
metK
Candidate S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.917
ahcY
Candidate Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.913
aspC
Aspartate transaminase.
     
  0.900
thrA
Candidate homoserine dehydrogenase.
  
 
 0.869
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
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